Muscle Specific Tyrosine Kinase (MuSK) Autoantibody - RIA

The RSR MuSK is intended for the quantitative determination of MuSK autoantibodies in human serum.

Autoantibodies to the MuSK protein have been found to lead to the failure of the neuromuscular transmission and muscle weakness associated with Acetylcholine receptor autoantibodies seronegative myasthenia gravis (MG).

MuSK is a skeletal muscle-protein that is essential for neuromuscular junction formation.

Measurement of these antibodies can be of considerable value in disease diagnosis and management.